Andrepositive raises the veil on research and a taboo subject in man.

Le diabète, la recherche et l'accompagnement.

Diabetes, Research and Support

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The research

Andrepositive raises the veil on research and a taboo subject in man.

Normally we diabetics from the point of view of the subjects that I treat for you, we are attentive to all that is done in the field of research on diabetes, but we are not taken or we forget that our system is affected by Diabetes and affects all parts of our body.

 

I want to talk to you about a subject that affects many older men. With aging, the prostate tissue expands and changes, causing enlargement of the gland (benign prostatic hyperplasia or BPH). A man over the age of 40 can see certain symptoms associated with prostate expansion, not understanding what justifies these changes, nor knowing that they can be treated. The cause of BPH remains unknown, although there may be links with the high-fat diet, family history and hormones. BPH does not match cancer !

 

Some men affected by BPH do not see any symptoms. However, if the expansion of the prostate compresses the urethra (the conduit that carries urine from the bladder to the outside of the body),

 

The following symptoms may be observed :

  • More frequent urination (day and night)
  • Inability to empty the bladder completely
  • Weak urine flow
  • Inability to delay urination
  • Difficulty in interrupting and starting urination
  • Incontinence (involuntary emission of urine)
  • Painful urination or presence of blood in the urine

 

What are the consequences on diabetes if the urine is not completely removed from the bladder and the bladder is too full ? The urine returns to your kidneys and causes you other problems. It is very important to protect your nostrils and your kidneys are in great demand and put to the test by poorly controlled diabetes. The more diabetes is badly controlled the more chance you have of needing dialysis or kidney transplant.

 

Here are some consequences:

 

In general, BPH is a relatively safe disorder, even in the presence of severe symptoms. Complications may occur, however, and may lead to potentially serious secondary problems:

 

• Cystitis / Bladder Infections / Urinary Infections. If the emptying of the bladder is incomplete, residual urine remaining stagnant will tend to become infected. While young men rarely suffer from urinary tract infections or cystitis, this kind of problem is not so unusual in older men and when this happens, it is usually a sign of BPH.

 

• Acute retention of urine. This condition may occur in the case of previously diagnosed, or even undiagnosed, BPH. The main signs are decreased ability or total inability to urinate, increased discomfort as well as swelling, sensitivity or pain in the abdomen. The placement of a catheter in the bladder then makes it possible to obtain a rapid relief.

 

• Chronic urine retention. Some men are unaware that they have a prostate problem, despite the fact that they have difficulty urinating. Over time, the urine accumulates and the bladder becomes desensitized. This causes an even greater amount of urine to accumulate in the bladder; With the months and years, the repression of the urine in the kidneys can damage important organs of the body.

 

• Hernia. Prolonged and repeated efforts at the time of urination may cause weakening at various places in the abdominal wall.

 

Currently to improve the passage of urine into the urethra, a medication can be taken to make the prostate prostate, but it does not work for everyone. There is only one way that is known to remedy this problem is surgery.

 

The surgeon using a camera enters the penis and will burn the prostate around the urinary channel in order to clear it to allow the urethra to resume its normal place. This surgery also requires a hospital stay of two days and a convalescence of one month without forcing and without having sexual intercourse. Moreover it is very painful.

 

For people who want to see the real-time procedure of the surgery, I put the video that I found on YouTube.

 

Animation video of the implantation intervention of the Medi Tate device :

Video of the implementation of the device in real time, sensitive soul abstain:

Video of a surgical operation of the operation to burn the walls of the prostate in real time, sensitive soul abstain:

But there will soon be a new procedure to treat benign prostatic hyperplasia or BPH. I was approached on December 22, 2016 to participate in research here in Canada at CIUSSS in Estrie, Fleurimont (CHUS Research Center) because I was on a list of conventional surgery for benign hypertrophy of the Prostate or BPH since November 2015.

 

This international, multicenter, prospective, Phase II, randomized, blind-controlled trial evaluated the efficacy and safety of the Implantable Temporary Device Nitinol (iTIND) DE Medi Tate in patients with symptomatic benign prostatic hyperplasia. Under the direction of lead researcher Dr. Mai Tu, Urologist.

 

This study plans to recruit approximately 190 men from different centers around the world, including up to 20 CHUS patients.

Participation in this study will last between 12 and 18 months, including 7 visits to the Research Center and implantation of the implantable Temporary Device Nitinol, or a placebo. This device will be installed on two out of three people.

 

Once the study physician confirms your eligibility for the study and agrees to participate, you will be assigned, through a computerized program, to one of the study groups Described below:

 

• Group 1 (the "study device group"): you will undergo the implantation procedure of the iTIND.

• Group 2 (the "control group") you will undergo a procedure in which the study doctor will insert a catheter into your urethra to simulate the implantation of the device being studied.

 

Neither you nor the study doctor will be able to choose your group.

 

I participated in this study and according to the group that I was assigned without knowing which group, I underwent the implantation of a device on January 10, 2017, today January 16, 2017 is going to me Remove it as the procedure requires, the implant will have stayed 5 to 7 days in me.

 

If I decided to do this research, it is first and foremost to advance research to find an alternative to surgery, because according to what I have read, there is much more to implant this temporary device (iTIND ) Of Medi Tate because the borrowing done by the device in the prostate would be permanent even if the prostate continues to grow and that to have the conventional surgery which consists of burning the walls of the prostate that surrounds the urethra and following A conversation I had with my brother-in-law who did conventional surgery and he has to repeat this procedure for the fourth time because the prostate continues to grow as he grow older.

 

For people who want to see what the Medi Tate device looks like, I will put the record of their site as a result of this presentation and also for the most curious two videos, one that will show you in real time the procedure of the surgery that Consists in burning the walls of the prostate and implanting the temporary implantable device Nitinol (iTIND) of Medi Tate, as well as a summary of the information form in search of the CHUS de Fleurimont.

 

I can not tell you when the device will be available implantable from Medi Tate for an alternative to surgery in the world, as it is only in second phase at the point of view test for validation by Health Canada. But I believe that this procedure will make its entry into the market in a fairly close time for the good of all people who have this problem of benign prostatic hyperplasia or BPH and for our diabetics this will offer us an opportunity to " Improve our condition without conventional surgery.

 

NB: I would like to thank, all nurses who are looking for their wonderful work and also Dr. Le Mai TU, Chief Urologist for excellent program works. I will give a brief account at the end of the study from today until the end of my participation in this research.

Here is the manufacturer's sheet;

 

Here is the manufacturer's sheet;

 

iTIND – Temporary Implantable Nitinol Device

 

The iTIND (Temporary Implantable Nitinol Device) is an innovative, non-surgical procedure that relieves BPH symptoms by creating new channels in the prostatic urethra through which urine can flow.

 

The iTIND provides immediate and long-term relief from symptoms with no side effects and without the need for drugs, surgery or a permanent implant.

 

The iTIND‘s clinical benefits are remarkable:

 

•Bloodless, non-surgical reshaping of the prostate

 

•Temporary implant, removed after only 5 days

 

•Eliminates the risk of sexual dysfunction

 

•Immediate symptoms relief, immediate return to daily life

 

•Simple, easy procedure - performed in minutes

 

The device is deployed in a very simple minimally invasive procedure. An iTIND insertion takes just 5 minutes. There are no catheters, no bleeding and the patient is able to immediately go back to his normal activities without affecting his lifestyle.

 

The iTIND stays 5 days in the urethra and clears obstructive tissue by exerting pressure from the inside, clearing the urethral path and enabling improved urination immediately following the procedure. The long-term effect is achieved by the reshaping of the prostate. Longitudinal channels are formed along the prostate and permanently expand the cross-section area of the prostatic urethra.

Optimal results are normally achieved within 3 months following the procedure.

 

5 days after implantation, the device is removed in just a few minutes.

 

Indication

 

The Temporary Implantable Nitino Device (iTIND) is indicated in patients suffering from Benign Prostatic Hyperplasia BPH. It forms longtitudinal channels in the bladder neck using targeted ischemia and is therefore a new solution for patients who are :

 

•Looking to preserve sexual function

 

•Looking for an alternative to drug therapy, or for whom drug therapy is not effective

 

•Looking for an alternative to surgery, or who cannot undergo surgery

 

•Looking for an immediate return to normal activities

 

•In acute retention

 

before iTIND treatment

after iTIND treatment

Step 1 : Insertion

 

The iTIND is deployed through rigid or flexible cystoscope within the prostatic urethra in a folded configuration. Once in place, the struts of the iTIND expand and exert radial force outwardly on the bladder neck and prostatic urethra at the 12, 5 and 7 o‘clock positions.

 

Step 3 : Expanded

 

The device was uniquely designed to ensure easy and accurate positioning, and to avoid trauma to sperm ducts and urethral sphincters, thereby eliminating the risk of retrograde ejaculation, erectile dysfunction or incontinence.

 

Step 2 : Positioning

 

This mechanism pushes obstructive tissue away from the urinary path and creates new longitudinal channels through which urine can flow freely. No catheter is required and the patient can immediately return to his daily life.

 

Step 4 : Device is removed after 5 days

 

At post-operative day 5, the device is completely removed through a foley catheter or a cystoscope. No implant is left in the body. No damage to sexual function. No incontinence. The new channels formed continue to provide relief for years to come.

 

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